Non-lamellar compositions of DOPE and P80
US8187629B2 · kind B2 · utility
12Cited by
2References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 21, 2005 |
| Grant date | May 29, 2012 |
| Priority date | — |
| Expiry date | Mar 3, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to particulate compositions comprising at least 50% of dioleoyl phosphatidyl ethanolamine (DOPE) and 1 to 50% of Polysorbate 80 (P80). All parts are by weight relative to the sum of the weights of a+b and the compositions comprise non-lamellar particles or form non-lamellar particles when contacted with an aqueous fluid. The compositions have advantageous stability and low toxicity and the invention also relates to pharmaceutical compositions thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.