Large-scale production of soluble hyaluronidase
US8187855B2 · kind B2 · utility
52Cited by
5References
16Claims
0Family size
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Key dates
| Filing date | Mar 6, 2009 |
| Grant date | May 29, 2012 |
| Priority date | — |
| Expiry date | Mar 6, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y302/01036
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided are methods for preparing large-scale preparations of soluble hyaluronidases. The methods employ cells that contain a plurality of active copies of nucleic acid encoding the soluble hyaluronidase and a plurality of feedings and temperature changes, whereby the encoded soluble hyaluronidase is secreted into the cell culture medium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.