Patent · US Active

Multicellular organisms derived from normal/nondiseased and diseased mammalian tissues

US8187857B2 · kind B2 · utility

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Assignee

Inventor

Key dates

Filing dateMar 17, 2005
Grant dateMay 29, 2012
Priority date
Expiry dateJan 18, 2028

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02W10/40
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention relates to pleomorphic cells (“morphotes”), which exhibit morphologic and genetic characteristics of both prokaryotic and eukaryotic cells, including resemblance to prokaryotic cells at the unicellular level, and resemblance to eukaryotic cells at the multicellular level due to their ability to self-organize in vitro into multicellular, mammalian tissue-like patterns consisting of tissue-like sheets, capillary-like networks, and trabecular (spongy) bone-like structures. Morphotes have a number of applications in the diagnostic medical, therapeutic medical, biological, biomaterials, bionanotechnological, and industrial fields.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.