Cell-chip and automatic controlled system capable of detecting conditions for optimizing differentiation of stem cell using mechanical stimulus
US8187863B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 24, 2008 |
| Grant date | May 29, 2012 |
| Priority date | — |
| Expiry date | Aug 17, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2035/1044
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided are a cell chip and a system thereof that are capable of detecting optimal conditions for stem cell differentiation by mechanical stimuli. The cell chip for cell differentiation experimentation includes a plurality of cell chambers for storing cells and culture media, cell and culture medium injection ports for transferring the cells and culture media to corresponding cell chambers, fine passages for moving the cells and the culture media injected into the cell and culture medium injection ports to the cell chambers, pneumatic injection ports for injecting pneumatic pressures applied to the cell chambers, and apertures having circular films for transferring the pneumatic pressures injected through the pneumatic injection ports to corresponding cell chambers. Here, at least two of the apertures may have different areas to vary the magnitude of pneumatic pressure applied to corresponding cell chambers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.