Means for obtaining avirulent leishmania promastigotes, promastigotes obtained, and the applications thereof
US8187870B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Feb 10, 2006 |
| Grant date | May 29, 2012 |
| Priority date | — |
| Expiry date | Sep 27, 2026 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to an expression vector of a gene coding for an antigenic protein of Leishmania promastigote, characterized in that it comprises a PSA gene insert in opposite orientation. The invention can be applied to the development of mutants under-expressing, or no longer expressing, genes coding for an antigenic protein of Leishmania promastigote, and to the therapeutic and/or vaccine-oriented uses thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.