Use of toll-like receptor-9 agonists, toll-like receptor-4 antagonists, and/or nuclear oligomerization domain-2 agonists for the treatment or prevention of toll-like receptor-4-associated disorders
US8188058B2 · kind B2 · utility
48Cited by
8References
3Claims
0Family size
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Key dates
| Filing date | Apr 17, 2008 |
| Grant date | May 29, 2012 |
| Priority date | — |
| Expiry date | Sep 19, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the use of a TLR9 agonist and/or a TLR4 antagonist and/or a NOD2 agonist for treatment or prevention of disorders involving TLR4 activation, such as systemic sepsis and necrotizing enterocolitis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.