Patent · US Active

Substituted 2-alkyl quinazolinone derivatives as PARP inhibitors

US8188103B2 · kind B2 · utility

13Cited by

2References

7Claims

0Family size

Assignee

Janssen Pharmaceuticals, Inc. · BE

Inventors

Marcel Jozef Maria Van der Aa · Kasterlee, BE
Albertus Henricus Maria Theresia Van Heertum · Turnhout, BE
Jacobus Alphonsus Josephus Van Dun · Kasterlee, BE
Maria Victorina Francisca Somers · Vosselaar, BE
Walter Boudewijn Leopold Wouters · Kapellen, BE

Key dates

Filing date	Dec 3, 2010
Grant date	May 29, 2012
Priority date	—
Expiry date	Dec 3, 2030

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions including compounds of formula (I)wherein R1, R3, L, X, Y and Z have defined meanings.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.