Imidazolic compounds and use thereof as alpha-2 adrenergic receptors
US8188126B2 · kind B2 · utility
1Cited by
8References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 24, 2010 |
| Grant date | May 29, 2012 |
| Priority date | — |
| Expiry date | Jun 16, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D233/64
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides methods of treating a memory deficiency in a subject in need of such treatment, where the methods comprise administering to a subject an effective amount of a compound of formula (1):wherein: R1 is hydrogen, fluorine or a methoxyl group, R1 being in position 2, 3, 4 or 5 of the aromatic carbocycle; R2 is hydrogen or a methyl group; R3 is hydrogen, a methyl group or an ethyl group; and their pharmaceutically acceptable acid addition salt as well as the isomers and the tautomers thereof. The memory deficiency may be correlated with a memory deficiency induced by scopolamine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.