Compounds that enhance Atoh1 expression
US8188131B2 · kind B2 · utility
17Cited by
15References
34Claims
0Family size
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Inventors
Key dates
| Filing date | Feb 9, 2009 |
| Grant date | May 29, 2012 |
| Priority date | — |
| Expiry date | Jul 8, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention generally provides compounds, pharmaceutical compositions, and methods for their use, which include methods that result in increased expression in an Atoh1 gene (e.g., Hath1) in a biological cell. More specifically, the invention relates to the treatment of diseases and/or disorders that would benefit from increased Atoh1 expression, e.g., a hearing impairment or imbalance disorder associated with a loss of auditory hair cells, or a disorder associated with abnormal cellular proliferation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.