Methods for the synthesis of dicarba bridges in organic compounds
US8188217B2 · kind B2 · utility
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29Claims
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Key dates
| Filing date | Feb 16, 2007 |
| Grant date | May 29, 2012 |
| Priority date | — |
| Expiry date | Feb 23, 2029 |
Classification
- Technology area (CPC —)General
Abstract
The present invention relates to methods for forming dicarba bridges in organic compounds. This involves the use of a pair of complementary metathesisable groups on the organic compound, and subjecting the compound to cross-metathesis under microwave radiation conditions. In an alternative, the compounds contain a turn-inducing group between the pair of cross-metathesisable groups to facilitate the cross-metathesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.