Bone morphogenic protein binding peptide
US8188219B2 · kind B2 · utility
9Cited by
8References
16Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jan 28, 2005 |
| Grant date | May 29, 2012 |
| Priority date | — |
| Expiry date | Sep 8, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/51
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2. BBP increases the over-all osteogenic activity of rgBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.