Antibodies to IL-6 and their uses

US8188235B2 · kind B2 · utility

Assignees

• PFIZER INC. · US
• Bristol-Myers Squibb Company · US

Inventors

• Arvind Rajpal · San Francisco, US
• Madhav Narasimha Devalaraja · Acton, US
• Kristopher Toy · San Jose, US
• Lan Yang · Burlingame, US
• Haichun Huang · Fremont, US
• Jun Zhang · Xiamen, CN
• Peter Brams · Sacramento, US
• Brigitte Devaux · Palo Alto, US
• David B. Passmore · Mountain View, US

Key dates

• Filing date: Jun 9, 2009
• Grant date: May 29, 2012
• Expiry date: Feb 25, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Antibodies and antigen-binding portions thereof that bind to human IL-6 are provided. Also provided are nucleic acids encoding such antibodies and antigen binding portions, methods of making such antibodies and antigen binding portions, compositions comprising such antibodies or antigen binding portions, and uses of such antibodies or antigen binding portions.