Creation of artificial internal ribosome entry site (IRES) elements
US8192984B2 · kind B2 · utility
4Cited by
18References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 3, 2002 |
| Grant date | Jun 5, 2012 |
| Priority date | — |
| Expiry date | Oct 14, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/67
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of producing a nucleic acid sequence having an adenine-rich nucleic acid block of at least 25 nucleotides in length is provided. The nucleic acid sequence that is produced is capable of initiating translation at an internal ribosome entry site (IRES) and the adenine-rich nucleic acid block comprises from 40 to 100 mol-% adenine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.