Epimerized derivatives of K5 polysaccharide with a very high degree of sulfation
US8193166B2 · kind B2 · utility
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4References
4Claims
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Key dates
| Filing date | Oct 1, 2010 |
| Grant date | Jun 5, 2012 |
| Priority date | — |
| Expiry date | Oct 1, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B37/0078
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A new method is described for the oversulfation of epiK5-N-sulfate to obtain an epiK5-amine-O-oversulfate with very high sulfation degree which, by subsequent N-sulfation, provides new epiK5-N,O-oversulfate-derivatives with a sulfation degree of at least 4, basically free of activity on the coagulation parameters and useful in the cosmetic or pharmaceutical field. Also described are new low molecular weight epiK5-N-sulfates useful as intermediates in the preparation of the corresponding LMW-epiK5-N,O-oversulfate-derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.