Inhibition of microtubule protrusion in cancer cells
US8193238B2 · kind B2 · utility
2Cited by
5References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 8, 2007 |
| Grant date | Jun 5, 2012 |
| Priority date | — |
| Expiry date | Oct 27, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention generally concerns microtubule protrusions in cancer cells, including detached cancer cells, and inhibition of the protrusions. In particular aspects, the inhibition of the protrusions interferes with attachment of the cell to a vessel wall, and in further aspects the cell is killed by forcing it to enter capillaries and be destroyed, for example by shearing. Inhibition by a variety of agents and methods is contemplated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.