Levodopa prodrug mesylate, compositions thereof, and uses thereof

US8193242B2 · kind B2 · utility

Assignee

• XENOPORT, INC. · US

Inventors

• Jia-Ning Xiang · Palo Alto, US
• Xuedong Dai · San Jose, US
• Cindy X. Zhou · Palo Alto, US
• Jianhua Li · Sunnyvale, US
• Mark Quang Nguyen · San Jose, US

Key dates

• Filing date: Jan 20, 2011
• Grant date: Jun 5, 2012
• Expiry date: Jan 20, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/13
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

(2R)-2-Phenylcarbonyloxypropyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate mesylate and crystalline form thereof, methods of making the same, pharmaceutical compositions thereof, and methods of using the same to treat diseases or disorders such as Parkinson's disease are provided.