Radiolabelled fluorobenzamide analogues, their synthesis and use in diagnostic imaging
US8193360B2 · kind B2 · utility
1Cited by
0References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 7, 2011 |
| Grant date | Jun 5, 2012 |
| Priority date | — |
| Expiry date | Apr 7, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/13
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Fluoroalkoxybenzamide compounds which selectively bind Sigma-2 receptors are disclosed. These compounds, when labelled with 18F, can be used as radiotracers for imaging of tumors by positron emission tomography (PET). In addition, these compounds, when labelled with 123I, can be used as radiotracers for imaging of tumors by single photon emission computed tomography (SPECT). Methods for synthesis of these compounds are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.