Patent · US Active

Plant expressing mammalian β1,4-galactosyltransferase and β1,3-glucuronyltransferase

US8193415B2 · kind B2 · utility

11Cited by

16References

21Claims

0Family size

Assignee

Stichting Dienst Landbouwkundig Onderzoek-PPO/PRI · NL

Inventors

Hendrikus Antonius Cornelis Bakker · Hannover, DE
Hendrik Jan Bosch · Utrecht, NL

Key dates

Filing date	Jul 16, 2010
Grant date	Jun 5, 2012
Priority date	—
Expiry date	Jul 16, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N15/8258
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to the field of glycoprotein processing in transgenic plants used as cost efficient and contamination safe factories for the production of recombinant biopharmaceutical proteins or pharmaceutical compositions comprising these. The invention provides a plant comprising a functional mammalian enzyme providing N-glycan biosynthesis that is normally not present in plants, said plant additionally comprising at least a second mammalian protein or functional fragment thereof that is normally not present in plants.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.