Methods for assessing the results of disc-based bioassays with standard computer optical drives
US8194514B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 2, 2009 |
| Grant date | Jun 5, 2012 |
| Priority date | — |
| Expiry date | Mar 18, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/545
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods and systems are described for assessing the results of a bioassay between probe biomolecules and target biomolecules using conventional optical disk drive. particular methods involve: bonding the probe biomolecules to a polycarbonate (PC) surface of an optical disk having digital data comprising error-detection redundancies recorded thereon: introducing the target biomolecules to the PC surface of the optical disk in a vicinity of the bonded probe biomolecules; processing the bioassay to alter a manner in which a read light from the optical disk interacts optically with the optical disk in a vicinity of positive bioassay results where the target biomolecules have bonded to the probe biomolecules; reading the digital data from the optical disk using the optical drive and using the error-redundancies to detect errors in the digital data read by the optical drive; mapping the detected errors to corresponding locations on the optical disk; and determining that positive bioassay results have occurred at the locations of the detected errors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.