Core-excited nanoparticles and methods of their use in the diagnosis and treatment of disease
US8197471B1 · kind B1 · utility
29Cited by
7References
51Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 21, 2011 |
| Grant date | Jun 12, 2012 |
| Priority date | — |
| Expiry date | Mar 21, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/904
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Core-excited nanoparticle thermotherapy (CENT), is an improved material for use in thermotherapy. The CENT method uses both core-exciting energy (including x-rays) and core-shell nanoparticles, specifically designed to absorb radiation in their core structure, then transfer energy from the core to the shell, to heat the outer shell of the nanoparticle. The heated nanoparticle then heats the surrounding region to a temperature sufficient to detect, affect, damage and/or destroy the targeted cell or material. CENT nanoparticles can be bound to targeting agents that deliver them to the region of the diseased cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.