Methods of radiofluorination of biologically active vectors

US8197793B2 · kind B2 · utility

Assignee

• GE HEALTHCARE AS · NO

Inventors

• Alan Cuthbertson · San Jose, US
• Magne Solbakken · Oslo, NO
• Joseph Maduabuchi Arukwe · Oslo, NO
• Hege Karlsen · Oslo, NO
• Matthias Eberhard Glaser · Norton, GB

Key dates

• Filing date: Mar 12, 2004
• Grant date: Jun 12, 2012
• Expiry date: Dec 20, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to conjugates of formula (V) or (VI): wherein X is —CO—NH—, —NH—, —O—, —NHCONH—, or —NHCSNH—; their use as radiopharmaceuticals, processes for their preparation, and synthetic intermediates used in such processes.