Regulation of mink in thymocytes and T lymphocytes
US8197817B2 · kind B2 · utility
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3References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 16, 2005 |
| Grant date | Jun 12, 2012 |
| Priority date | — |
| Expiry date | May 12, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to compositions and methods used to assess and alter the expression and activity of MINK in cells of the immune system, particularly thymocytes and T lymphocytes. The methods and compositions are used in a variety of clinical applications including vaccination, treatment of cancer, infectious disease, allergy, and transplantation. Screening methods are provided to identify inhibitors of MINK and susceptibility to effects of under- or over-expression of MINK.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.