Self-emulsifying active substance formulation and use of this formulation

US8197829B2 · kind B2 · utility

Assignee

• Abbott Laboratories · US

Inventors

• Gunther Berndl · Herxheim, DE
• Jorg Breitenbach · Mannheim, DE
• Robert Heger · Heidelberg, DE
• Michael Stadler · Seelow, DE
• Peter Wilke · Ludwigshafen, DE
• Jörg Rosenberg · Ellerstadt, DE

Key dates

• Filing date: May 29, 2001
• Grant date: Jun 12, 2012
• Expiry date: Oct 30, 2026

Classification

• Technology area (CPC —): General

Abstract

The present invention relates to self-emulsifying formulations based on an active ingredient component and a formulation base with a lipid component and with a binder component and to the use of this formulation as dosage form in the life science sector. The invention also describes a process for producing self-emulsifying formulations by mixing the formulation components to form a plastic mixture and, where appropriate, to manufacture the formulations as dosage form advantageously by use of melt extrusion. The formulations spontaneously form emulsions in water or aqueous media.