Method for the chemo-selective enzymatic hydrolysis if a diester compound for preparing a monoester monoacid compound
US8198054B2 · kind B2 · utility
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Key dates
| Filing date | Jan 22, 2008 |
| Grant date | Jun 12, 2012 |
| Priority date | — |
| Expiry date | Dec 13, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/62
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This disclosure relates to the synthesis of the compound of formula (I) according to Scheme A below:in which R1, R2 and R3, which may be identical or different, represent, individually and independently, an alkyl group, characterized by an enzymatic hydrolysis reaction that involves placing the compound of formula (II) in contact with an enzyme that performs a chemoselective hydrolysis of only one of the two ester functions of the compound of formula (II) to obtain the compound of formula (I).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.