Hydrolases, nucleic acids encoding them and methods for making and using them

US8198062B2 · kind B2 · utility

Assignee

• DSM IP ASSETS B.V. · NL

Inventors

• Timothy Hitchman · Encinitas, US
• Christopher L. G. Dayton · Mount Kisco, US
• Katie Kline · San Diego, US
• Jonathan Lyon · San Diego, US
• Mark A. Wall · San Diego, US
• Nelson R. Barton · San Diego, US

Key dates

• Filing date: Aug 29, 2008
• Grant date: Jun 12, 2012
• Expiry date: Jul 3, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y301/01021
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided are hydrolases, including lipases, saturases, palmitases and/or stearatases, and polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides. Further provided are polypeptides, e.g., enzymes, having a hydrolase activity, e.g., lipases, saturases, palmitases and/or stearatases and methods for preparing low saturate or low trans fat oils, such as low saturate or low trans fat animal or vegetable oils, e.g., soy or canola oils.