Methods of suppressing microglial activation
US8198234B2 · kind B2 · utility
1Cited by
8References
8Claims
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Key dates
| Filing date | May 13, 2010 |
| Grant date | Jun 12, 2012 |
| Priority date | — |
| Expiry date | May 13, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of suppressing the activation of microglial cells in the Central Nervous System (CNS), methods of ameliorating or treating the neurological effects of cerebral ischemia or cerebral inflammation, and methods of combating specific diseases that affect the CNS by administering a compound that binds to microglial receptors and prevents or reduces microglial activation are described. Also described are methods of screening compounds for the ability to suppress or reduce microglial activation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.