Variants of C-type natriuretic peptide
US8198242B2 · kind B2 · utility
29Cited by
13References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 20, 2010 |
| Grant date | Jun 12, 2012 |
| Priority date | — |
| Expiry date | Jun 11, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides variants of C-type natriuretic peptide (CNP), pharmaceutical compositions comprising CNP variants, and methods of making CNP variants. The CNP variants are useful as therapeutic agents for the treatment of diseases responsive to CNP, including but not limited to bone-related disorders, such as skeletal dysplasias (e.g., achondroplasia), and vascular smooth muscle disorders (e.g., restenosis and arteriosclerosis).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.