Substituted heteroaryl pyridopyrimidone derivatives
US8198287B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Jun 18, 2009 |
| Grant date | Jun 12, 2012 |
| Priority date | — |
| Expiry date | Dec 20, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D239/70
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof are disclosed and claimed.Wherein m, n, o, Y, Z, R1, R2, R3, R4, R5 R6 and R7 are as described herein. Also disclosed are the salts of compounds of formula (I). The invention relates also to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3β, such as Alzheimer disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.