Compositions and methods with enhanced therapeutic activity
US8198302B2 · kind B2 · utility
2Cited by
8References
8Claims
0Family size
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Key dates
| Filing date | Mar 1, 2004 |
| Grant date | Jun 12, 2012 |
| Priority date | — |
| Expiry date | Jul 24, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel quinone and catechol compositions, compositions containing prodrugs of quinone and catechol compositions, and methods of use for the treatment of solid tumor cancers and other vascular proliferative disorders. The disclosure particularly relates to the discovery of dual activity agents capable of generating both a vascular targeting effect and direct tumor cell cytotoxicity in order to achieve an enhanced anti-tumor response in a patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.