Methods for modulating macrophage proliferation in ocular disease using polyamine analogs
US8198334B2 · kind B2 · utility
0Cited by
26References
11Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Feb 22, 2005 |
| Grant date | Jun 12, 2012 |
| Priority date | — |
| Expiry date | Mar 28, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/164
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods for modulating macrophage proliferation in an individual afflicted with or at risk for an ocular disease such as ARMD are provided. The methods employ a polyamine analog, or salt or protected derivative thereof. Macrophage proliferation has been implicated in a number of serious disorders, including ARMD. The invention also provides methods for aiding diagnosis and monitoring therapy of an ocular disease such as ARMD.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.