Compounds for the treatment of hepatitis C

US8198449B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Richard Pracitto · San Diego, US
• John F. Kadow · Wallingford, US
• John A. Bender · Middletown, US
• Brett R. Beno · Cromwell, US
• Katharine A. Grant-Young · Madison, US
• Ying Han · Cheshire, US
• Piyasena Hewawasam · Middletown, US
• Andrew Nickel · San Marino, US
• Kyle E. Parcella · Wallingford, US
• Kap-Sun Yeung · Madison, US
• Louis S. Chupak · Old Saybrook, US

Key dates

• Filing date: Aug 28, 2009
• Grant date: Jun 12, 2012
• Expiry date: May 14, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/048
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.