Method of hormone extraction using digital microfluidics
US8202736B2 · kind B2 · utility
94Cited by
15References
43Claims
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Key dates
| Filing date | Feb 26, 2009 |
| Grant date | Jun 19, 2012 |
| Priority date | — |
| Expiry date | Oct 3, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2001/4061
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of extracting hormones from a biological sample using digital microfluidic arrays is provided. Biological samples containing hormones are dried on a digital microfluidic array, lysed by a lysing solvent, dried, subsequently dissolved in a polar solvent, and further purified in an extraction step in which droplets are transported through a volume of non-polar solvent. The method disclosed herein provides the distinct advantage of an automated sample preparation method that is capable of extracting hormones from low sample volumes with excellent precision and recovery.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.