Substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof

US8202895B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Ulf Bruggemeier · Leichlingen, DE
• Chantal Fürstner · Neheim, DE
• Volker Geiβ · Ratingen, DE
• Joerg Keldenich · Wuppertal, DE
• Armin Kern · Wuppertal, DE
• Martina Delbeck · Essen, DE
• Peter Kolkhof · Wuppertal, DE
• Axel Kretschmer · Wuppertal, DE
• Elisabeth Pook · Wuppertal, DE
• Carsten Schmeck · Wuppertal, DE
• Hubert Trübel · Wuppertal, DE

Key dates

• Filing date: Mar 18, 2010
• Grant date: Jun 19, 2012
• Expiry date: Apr 16, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to new, substituted 2-acetamido-5-aryl-1,2,4-triazolones, to processes for preparing them, to their use alone or in combinations for the treatment and/or prevention of diseases and also to their use for the production of medicaments for the treatment and/or prevention of diseases, more particularly for the treatment and/or prevention of cardiovascular disorders.