Synthetic RNA-based agonists of TLR7
US8202974B2 · kind B2 · utility
4Cited by
1References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 10, 2010 |
| Grant date | Jun 19, 2012 |
| Priority date | — |
| Expiry date | Feb 10, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/51
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the therapeutic use of stabilized oligoribonucleotides as immune modulatory agents for immune therapy applications. Specifically, the invention provides RNA-based oligoribonucleotides with improved nuclease and RNase stability and that selectively induce immune modulatory activity through TLR7.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.