Process for the preparation of 2-fluoroadenine
US8202991B2 · kind B2 · utility
1Cited by
2References
14Claims
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Key dates
| Filing date | Dec 11, 2008 |
| Grant date | Jun 19, 2012 |
| Priority date | — |
| Expiry date | Apr 19, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D473/40
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the preparation of 2-fluoroadenine with a purity of at least 98% (HPLC Area) is presented. Such very high purity degree of at least 98% (HPLC Area) is obtained directly on the crude product after reacting 2,6-diaminopurine in an amount of anhydrous fluorinating agent; heating the resulting reaction mixture; quenching the heated reaction mixture; separating the solid obtained thereby; and washing and separating the solid, without recrystallization and/or any further purification steps.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.