Processes for producing monoammonium succinate from fermentation broths containing diammonium succinate, monoammonium succinate and/or succinic acid, and conversion of monoammonium succinate to succinic acid

US8203021B2 · kind B2 · utility

Assignee

• BioAmber S.A.S. · CA

Inventors

• Olan S. Fruchey · Port Aransas, US
• Brian T. Keen · Charleston, US
• Brooke A. Albin · Charleston, US
• Nye A. Clinton · Hurricane, US
• Dilum Dunuwila · Okemos, US
• Bernard D. Dombek · Charleston, US

Key dates

• Filing date: Aug 17, 2011
• Grant date: Jun 19, 2012
• Expiry date: Aug 17, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C51/46
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Processes for making monoammonium succinate (MAS) and/or succinic acid (SA) from either a clarified diammonium succinate (DAS)-containing fermentation broth or a clarified MAS-containing fermentation broth include (a) distilling the broth to form an overhead that includes water and optionally ammonia and a liquid bottoms that includes MAS or SA; (b) cooling and/or evaporating the bottoms and optionally adding an antisolvent to the bottoms to attain a temperature and composition sufficient to cause the bottoms to produce a solid portion that contains MAS or SA in contact with a liquid portion; (c) separating the solid portion from the liquid portion; and (d) recovering the solid portion.