Injection of fibrin sealant using reconstituted components in spinal applications
US8206448B2 · kind B2 · utility
3Cited by
56References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 17, 2005 |
| Grant date | Jun 26, 2012 |
| Priority date | — |
| Expiry date | Dec 11, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/38
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, wherein the fibrinogen, the activating compound or both has been reconstituted with a solution containing at least one additive, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.