Patent · US Active

Modified bacteriocins and methods for their use

US8206971B2 · kind B2 · utility

3Cited by

9References

7Claims

0Family size

Assignee

AvidBiotics Corp. · US

Inventors

Dean M. Scholl · Burlingame, US
Steven R. Williams · Colorado Springs, US

Key dates

Filing date	Feb 5, 2010
Grant date	Jun 26, 2012
Priority date	—
Expiry date	Jul 19, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/74
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Modified forms of naturally occurring bacteriocins, such as the R-type pyocins of Pseudomonas aeruginosa, are disclosed as are methods for producing them in GRAS organisms. The bacteriocins are modified at the ends of their tail fibers in a region responsible for binding specificity and affinity to their cognate binding partners, or receptors, such as those on the surface of bacteria. Methods for the use of the modified bacteriocins, such as to bind receptors, including virulence or fitness factors, on the surfaces of bacteria, are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.