Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
US8207153B2 · kind B2 · utility
43Cited by
41References
6Claims
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Key dates
| Filing date | Mar 25, 2010 |
| Grant date | Jun 26, 2012 |
| Priority date | — |
| Expiry date | Jun 3, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds that inhibit P13Kδ activity, including compounds that selectively inhibit P13Kδ activity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (P13Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation in which P13Kδ plays a role in leukocyte function, using the compounds also are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.