Aryloxypropanolamines, methods of preparation therof and use of aryloxypropanolamines as medicaments

US8207174B2 · kind B2 · utility

Assignee

• 4SC AG · DE

Inventors

• Stefan Tasler · Hanerau-Hademarschen, DE
• Daniel VITT · Germering, DE
• Kristina Wolf · Kottgeisering, DE
• Andrea Aschenbrenner · Munich, DE
• Peter Ney · Grevenbroich, DE

Key dates

• Filing date: Jan 22, 2008
• Grant date: Jun 26, 2012
• Expiry date: Jul 24, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D495/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to novel aryloxypropanolamines. The invention also relates to the pharmaceutically acceptable salts and solvates containing said compounds, methods for the preparation thereof and to respective synthetic intermediates. Said compounds have agonistic activity at β3 adrenergic receptors and are useful for treatment of ailments influenced by activation of β3 adrenergic receptors.