Patent · US Active

Method for treating neurological and neuropathic diseases using rho kinase inhibitor compounds

US8207195B2 · kind B2 · utility

36Cited by
0References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 26, 2009
Grant dateJun 26, 2012
Priority date
Expiry dateJun 4, 2030

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/55
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention is directed to methods of preventing or treating neurological or neuropathic diseases or conditions associated with excessive inflammation, neurodegeneration, neuro-remodeling, and axonal/neurite retraction. Particularly, this invention relates to methods treating neurological or neuropathic diseases such as cerebral ischemia, stroke, neuropathic pain, spinal cord injury, Alzheimer's disease, and multiple sclerosis, using novel rho kinase inhibitor compounds. The method comprises identifying a subject in need of the treatment, and administering to the subject an effective amount of a novel rho kinase inhibitor compound to treat the disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.