Ion channel modulating activity I
US8207219B2 · kind B2 · utility
13Cited by
32References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 19, 2010 |
| Grant date | Jun 26, 2012 |
| Priority date | — |
| Expiry date | Jan 19, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D207/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods, compositions, dosing regimes, and routes of administration for the treatment or prevention of arrhythmias. In these methods, early afterdepolarizations and prolongation of QT interval may be reduced or eliminated by administering ion channel modulating compounds to a subject in need thereof. The ion channel modulating compounds may be cycloalkylamine ether compounds, particularly cyclohexylamine ether compounds. Also described are compositions of ion channel modulating compounds and drugs which induce early afterdepolarizations, prolongation of QT interval and/or Torsades de Pointes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.