Immobilization of membrane proteins onto supports via an amphiphile
US8207263B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 13, 2007 |
| Grant date | Jun 26, 2012 |
| Priority date | — |
| Expiry date | May 11, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K17/06
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention pertains to the field of membrane protein immobilization onto supports. It relates to a product comprising a support and at least one membrane protein attached to the surface thereof, characterized in that said membrane protein is attached to said support using an amphiphilic molecule with which said membrane protein is complexed. It also relates to a process for preparing such product, as well as to various applications in the fields of diagnosis, drug design and biotechnologies. It further relates to a kit, together with a functionalized amphiphilic molecule, for preparing a product according to the invention comprising a support and an amphiphilic molecule, wherein the amphiphilic molecule and the support interact through a hydrophobic bond, an ionic bond, a specific bond or a covalent bond.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.