Tetrahydroquinolines for use as modulators of the mitotic motor protein Eg5

US8207345B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Kai Schiemann · Darmstadt, DE
• David Bruge · Frankfurt am Main, DE
• Hans-Peter Buchstaller · Griesheim, DE
• Ulrich Emde · Darmstadt, DE
• Dirk Finsinger · Darmstadt, DE
• Christiane Amendt · Mühltal, DE
• Frank Zenke · Darmstadt, DE

Key dates

• Filing date: Jun 2, 2006
• Grant date: Jun 26, 2012
• Expiry date: Sep 3, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula (I), in which W, R, R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in Claim 1, can be employed, inter alia, for the treatment of tumors.