Patent · US Active

Benzoic acid derivatives as human papilloma virus inhibitors

US8207373B2 · kind B2 · utility

1Cited by
1References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 18, 2007
Grant dateJun 26, 2012
Priority date
Expiry dateApr 16, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D295/135
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

HPV inhibitors with formula (I) where G1 represents a hydrocarbonated bond or chain possibly substituted by one or two alkyl groups, G2 represents a group (see formula Ia+Ib) or R represents a hydrogen, an alkyl, halogenoalkyl, or a prodrug radical such as carbamate, acetyl or dialkylaminomethyl, G represents a bond or a hydrocarbonated chain possibly substituted by one or two alkyls, W represents an oxygen or sulphur, R1 and R2 each represent a group chosen from among hydrogen, halogen, hydroxyl, thio, alkoxy, halogenoalkoxy, alkylthio, halogenoalkylthio, amino, monoalkylamino, dialkylamino, cycloalkyl, alkyl or halogenoalkyl, R3 represents an acid or a prodrug radical of the acid function or a bioisostere of the acid function, A represents an aryl, cycloalkyl, cycloalkenyl or a heterocycle, each possibly substituted, and B represents an aryl or a heterocycle with 6 chains, each possibly substituted, and pharmaceutically acceptable salts.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.