Biological targeting compositions and methods of using the same

US8211656B2 · kind B2 · utility

Assignee

• THE INVENTION SCIENCE FUND I, LLC · US

Inventors

• Roderick A. Hyde · Redmond, US
• Muriel Y. Ishikawa · Livermore, US
• Edward K.Y. Jung · Bellevue, US
• William Gates · Redmond, US
• Alois A. Langer · Pasadena, US
• Eric C. Leuthardt · Chesterfield, US
• Royce A. Levien · Lexington, US
• Clarence T. Tegreene · Bellevue, US
• Thomas A. Weaver · San Mateo, US
• Charles Whitmer · North Bend, US
• Lowell L. Wood, JR. · Bellevue, US
• Victoria Y.H. Wood · Livermore, US

Key dates

• Filing date: Aug 13, 2008
• Grant date: Jul 3, 2012
• Expiry date: Dec 18, 2030

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/555
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Modified red blood cells are described. In an embodiment, the modified red blood cell includes a target-binding agent. Targeted delivery of imaging agents, drugs, and peptide and protein pharmaceuticals using modified red blood cells are described. Processes for preparing the modified red blood cells, pharmaceutical and diagnostic compositions containing the same and methods of diagnosis and treatment involving the modified red blood cells are described.