Naphthamide derivatives as multi-target protein kinase inhibitors and histone deacetylase inhibitors
US8211901B2 · kind B2 · utility
8Cited by
11References
18Claims
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Key dates
| Filing date | May 21, 2010 |
| Grant date | Jul 3, 2012 |
| Priority date | — |
| Expiry date | Nov 10, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Isolated compounds of formula I:and stereoisomers, enantiomers, diastereomers, and pharmaceutically acceptable salts thereof are described, as well as processes for production, and methods of use of these compounds and compositions thereof for the treatment of diseases associated with abnormal protein kinase activities and/or abnormal histone deacetylase activities including, for example, inflammatory diseases, autoimmune diseases, cancer, neurological and neurodegenerative diseases, cardiovascular diseases, metabolic disease, allergies and asthma and/or hormone-related diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.