Patent · US Active

5-phenyl-isoxazole-3-carboxamide derivatives as TRPV1 modulators

US8211927B2 · kind B2 · utility

2Cited by

0References

13Claims

0Family size

Assignee

MSD OSS B.V. · NL

Inventors

Andrew Roughton · Port Hope, CA
Koc-Kan Ho · Mount Kisco, US
Michael Ohlmeyer · Plainsboro, US
Irina Neagu · Plainsboro, US
Steven G. Kultgen · Hillsborough Township, US
Nasrin Ansari · Monmouth Junction, US
Yajing Rong · Monmouth Junction, US
Paul Ratcliffe · Lanark, GB
Ronald Palin · Banton, GB

Key dates

Filing date	Jul 31, 2008
Grant date	Jul 3, 2012
Priority date	—
Expiry date	Jul 31, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D261/18
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to isoxazole-3-carboxamide derivative having the general Formula (I), or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of said isoxazole-3-carboxamide derivatives for the treatment of TRPV1 mediated disorders, such as acute and chronic pain disorders, acute and chronic neuropathic pain, acute and chronic inflammatory pain, respiratory diseases, and lower urinary tract disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.