Pyrroles having hypolipidemic hypocholesteremic activities, process for their preparation and pharmaceutical compositions containing them and their use in medicine

US8212057B2 · kind B2 · utility

Assignee

• Cadila Healthcare Ltd. · IN

Inventors

• Braj Bhushan Lohray · Hyderabad, IN
• Vidya Bhushan Lohray · Hyderabad, IN
• Vijay Kumar Gajubhai Barot · Sayla, IN
• Saurin Raval · Sayla, IN
• Preeti Raval · Sayla, IN
• Sujay Basu · Mumbai, IN

Key dates

• Filing date: Jul 25, 2002
• Grant date: Jul 3, 2012
• Expiry date: Jul 5, 2026

Classification

• Technology area (CPC G): Physics
• CPC primary: G09G2360/122
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel substituted pyrrole compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. This invention particularly relates to novel substituted pyrrole compounds of the general formula (I), their analogs, their derivatives, their polymorphs, their tautomeric forms, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and their pharmaceutical compositions containing them. The invention also relates to the process for preparing such compounds, a composition containing such a compound and the use of such a compound and composition in medicine. The compounds lower triglyceride levels in blood and may be useful in the treatment of obesity, hyperlipidaemia, hypercholesteremia, syndrome X and diabetes.