Genetic polymorphisms associated with cardiovascular diseases, methods of detection and uses thereof
US8216786B2 · kind B2 · utility
12Cited by
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30Claims
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Key dates
| Filing date | Jul 9, 2009 |
| Grant date | Jul 10, 2012 |
| Priority date | — |
| Expiry date | Aug 20, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/172
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods based on genetic polymorphisms that are associated with cardiovascular diseases, particularly coronary heart disease (especially myocardial infarction) or hypertension. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.